Delirium: A Comprehensive Review for Nursing Diagnosis, Management, and Intervention Controls

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Hnan Nassir Hossin Mobarkyi,Lajwa Talaq ,Mona Mohamad Farahan Alhoyan Alsharariy,Mousaed Addh Aoued Alotibi ,Moneaa Hasher Abdulali Alotaibi,Hanan Eid Rashed Alghanami ,Samirah Mahal Hamad Alanazi,Sarah Mohammad Abdul Rahman Alotaibi,Anoud Mohammed Alotaibi , Sami Sabih T Alshararisasalsharary, Abdulaziz Tabshan Nughaymish Alsharari,Ahmed Jadullah Luwayfi Alsharari,Nada Saleh Alhosini,Mohammed Gharib Al-Harbi,Mufleh Aqeel Mufleh Al-Anazi

Abstract

Background: Delirium is an acute neuropsychiatric syndrome characterized by altered attention, consciousness, and cognitive function, often affecting elderly individuals. It arises from underlying medical conditions and is associated with significant morbidity, mortality, and healthcare costs. The condition is multifactorial, with predisposing and precipitating factors contributing to its onset. Despite its clinical importance, delirium is frequently underdiagnosed, particularly in its hypoactive form, leading to delayed intervention and poor outcomes.


Aim: This review aims to provide a comprehensive overview of delirium, focusing on its diagnosis, management, and intervention strategies. It emphasizes the importance of early detection, multidisciplinary collaboration, and evidence-based approaches to improve patient outcomes.


Methods: The review synthesizes current literature on delirium, including its pathophysiology, risk factors, diagnostic criteria, and management strategies. It highlights the use of validated assessment tools such as the Confusion Assessment Method (CAM) and discusses non-pharmacologic interventions, including the Hospital Elder Life Program (HELP). Pharmacologic treatments are explored in specific contexts, such as hyperactive delirium and substance withdrawal.


Results: Delirium is a complex condition requiring a multifaceted approach for effective management. Non-pharmacologic interventions, such as environmental modifications, reorientation strategies, and sleep promotion, are foundational. Pharmacologic treatments, primarily antipsychotics, are reserved for severe cases. Early detection and prevention are critical, as delirium is associated with prolonged hospital stays, increased mortality, and significant healthcare costs.


Conclusion: Delirium is a serious yet often preventable condition that necessitates a proactive, interprofessional approach. Early identification, targeted interventions, and continuous monitoring are essential to mitigate its impact. While pharmacologic treatments have limited roles, non-pharmacologic strategies remain the cornerstone of management. Future research should focus on refining diagnostic tools and exploring effective pharmacologic options.

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