The Impact of Omics Technologies on Laboratory Medicine: Transformations in Precision and Personalized Healthcare

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Belgaith Othman Belgaith Alsefri,Ghalib Ali Ahmed Almaqadi ,Khalid Moadi Assiri, Mousa Mohmad Abdo Alhassni, Ali Ahmed Ali Alsayed,Ibrahim Ali Ahmed Alnashery, Ahmed Belqasem Nasser Alsolbi , Noori Mabred Noori Alsayed, Darweesh Othman Ahmed Alsffri, Abubakr Ali Alsohbi,Mohammad Abduh Jaber Alhelaly,Merai Ali Muabrid Alsayed,Khadijah Ahmed Ali Alshuqayfi

Abstract

Background: Integrating omics technologies—genomics, proteomics, metabolomics, and transcriptomics—into laboratory medicine is revolutionizing the diagnostic landscape. These technologies facilitate precision and personalized medicine by enabling the categorization of patients based on their unique biological profiles, leading to more effective treatment strategies.


Methods: This review systematically examines the role of omics technologies in laboratory medicine, focusing on their applications in clinical diagnostics and patient management. A comprehensive literature search was conducted across various databases to identify relevant studies and innovations in omics technologies from their inception to 2023.


Results: The findings reveal that omics technologies significantly improve diagnostic accuracy and treatment efficacy, particularly in oncology, cardiology, and metabolic disorders. For instance, next-generation sequencing (NGS) has identified genetic mutations associated with specific cancers, allowing for targeted therapies. Additionally, the integration of artificial intelligence with omics data enhances predictive modeling, further personalizing patient care.


Conclusion: Omics technologies are essential for advancing laboratory medicine, offering transformative capabilities that enhance patient outcomes through tailored treatment plans. As these technologies continue to evolve, ongoing research and interdisciplinary collaboration are vital to fully realize their potential in clinical settings.

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